Wednesday, Mar 25, 2015

Precisely measure and map both 5hmC and 5mC at single base resolution

Wisegene 5hmC TAB-Seq Kit and 5hmC/5mC TAB-Array Kit (compatible to Infinium 450K Array)

The 5hmC TAB-Seq Kit can be used to prepare genomic DNA to differentiate 5-hydroxylmethylcytosine (5hmC) from 5-methylcytosine (5mC) for subsequent sequencing applications by converting 5mC to 5-carboxylcytosine (5caC) while keeping 5hmC protected.

Each kit contains enough reagents for up to 5 genome-wide or 15 loci-specific sequencing reactions based on recommended protocols.

The TAB-Array Kit can be used to prepare genomic DNA by converting 5mC to 5-carboxylcytosine (5caC) while keeping 5hmC protected. This approach is used to differentiate 5-hydroxylmethylcytosine (5hmC) from 5-methylcytosine (5mC) for subsequent genome-wide 5hmC/5mC detections using Infinium 450K array or other array/enrichment platforms.

Each kit contains enough reagents for up to 10 samples based on recommended protocols.

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